KMID : 0385920160270010134
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Journal of the Korean Society of Emergency Medicine 2016 Volume.27 No. 1 p.134 ~ p.138
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Case of Ischemic Colitis Associated with Pseudoephedrine
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Yun Su-Hyun
Suh Seong-O Park Chae-A Choi Bo-Yoon Kwon Min-Gu Jang Min-Ho Gwak Jin-Wuk Jeong Da-Sol Shin Dong-Hwan Kwon Sang-Jae Choi Da-Woori Lee Je-Seung
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Abstract
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Ischemic colitis is the consequence of a sudden reduction in colon blood supply, which in turn results in ischemic injury. The splenic flexure and rectosigmoid junction are the areas most often affected. Ischemic colitis occurs with greater frequency in the elderly and is caused by various medications and procedures. Pseudoephedrine acts as a vasoconstrictor directly affecting adrenal receptors of nasal mucous membrane. Pseudoephedrine occasionally causes vascular insufficiency due to intense vasoconstriction, even at standard doses. Ischemic colitis associated with pseudoephedrine has been reported in other countries,, but it has never been reported in Korea. In this paper, we describe 3 cases of ischemic colitis that occurred after taking pseudoephedrine for nasal congestion.
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KEYWORD
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Ischemic colitis, Pseudoephedrine, Gastrointestinal hemorrhage
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